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It isn't the leg where the toe was amputated. I am noticing an increase in swelling up the leg this morning (Sunday) and have an emergent call into the vet. We are in the country so we might need to drive him into Pittsburgh to see a specialist. Poor buddy. He is certainly stoic about it all. His leg is definitely hot to the touch and I have told our vet this. Would bone diseae show up on normal films or is there a special x-ray for that?
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What kind of cancer was found with the amputated toe? Even if it isn't the same leg it is quite possible that it could have spread to another bone. Bone cancer should show up on normal xrays so long as the person viewing the xrays knows what to look for. Usually it is very characteristic, however if the xrays are taken early it might be easy to miss. That is why it is best to have an oncologist look at the films. Hopefully you will hear back from the vet. If the swelling is increasing and the leg is wrapped it could damage the leg by causing the bandage to be too tight. Is his leg hard where the swelling is?
Because the leg is hot to the touch it could be a bone infection or it could be because the bandage is too tight. I would also recommend a full blood panel and cbc. The bloodwork might indicate an infection which could be the cause of the swelling and needs to be treated through appropriate antiobiotics not pain relievers. Are you noticing any discharge?